The Reformed apologist cannot agree at all with the methodology of the natural man. Disagreeing with the natural man’s interpretation of himself as the ultimate reference-point, the Reformed apologist must seek his point of contact with the natural man in that which is beneath the threshold of his working consciousness, in the sense of deity which he seeks to suppress. And to do this the Reformed apologist must also seek a point of contact with the systems constructed by the natural man. But this point of contact must be in the nature of a head-on collision. If there is no head-on collision with the systems of the natural man there will be no point of contact with the sense of deity in the natural man. So also, disagreeing with the natural man on the nature of the object of knowledge, the Reformed apologist must disagree with him on the method to be employed in acquiring knowledge. According to the doctrine of the Reformed faith all the facts of nature and of history are what they are, do what they do and undergo what they undergo, in accord with the one comprehensive counsel of God. All that may be known by man is already known by God. And it is already known by God because it is controlled by God.

– Cornelius Van Til, The Defense of the Faith p.120-121